A conference to gather an overview of the status and future prospects of astrophysics and cosmology with a multimessenger approach. The conference will feature only plenary sessions on the following topics: astrophysics with electromagnetic waves, astrophysics with gravitational waves, astroparticle physics and neutrino astrophysics, nuclear astrophysics, cosmology. The conference was originally planned for 2020 and moved to 2021 because of the Covid-19 emergency situation.