ISC-2022 is a FIVE-week school designed to be an introduction to different key aspects of Data Science and Machine Learning in different branches of science (chemistry, food & feed, physics, environmental, political economics, etc). ISC-2022 addresses BSc, MSc, PhD students/post-docs, associate professors, etc. who want to acquire or refresh basic knowledge on multivariate data analysis from different disciplines. ISC-2022 is also addressed to researchers working in industry or research laboratories wanting to implement multivariate data analysis in their daily research environment.