This conference will highlight the recent achievements and challenges in understanding nonlinear multiscale phenomena in astrophysical plasmas, bringing together theorists, simulators and observers who work on both astrophysical and space plasmas. The subjects will include the microphysics of shock acceleration and long range cosmic ray feedback in galaxies, the properties of reconnection in astrophysical and space plasmas, including its effect on particle acceleration, and the physics of turbulent cascades in magnetized plasmas of galaxy clusters and accretion disks.