This long program will focus on the newest development of UQ methodologies and how they can improve AI systems and provide solutions to modeling complex systems. It will also give an outlook on future UQ directions and challenges. Through all the activities proposed, the program will bring together interested parties, researchers, practitioners, and students, from different areas of UQ, promote communication, and further break down the barriers between disciplines. The program also has a significant mentoring component, which connects researchers and students at different career stages.