The summer school aims to expose participants to formal methods that can facilitate principled scientific discovery. The school will cover some of the basic automated statistical inference (in the form of machine learning techniques) and reasoning methods that are commonly used in scientific discovery, as well as novel techniques developed to tackle open questions and issues. This summer school will address novel computational methods for scientific discovery and focus on fusing axiomatic knowledge and experimental data to enable principled derivations of models of natural phenomena along with certificates of the consistency of these models with background knowledge specified as axioms.