The 5-day workshop, "Space-time Approaches to PDE Solvers: Unlocking the Power of Co-Design'', will bring together a diverse group of leading international experts in numerical analysis, scientific computing, and hardware-software integration to review and explore the cutting-edge developments and challenges in the simulation of complex PDEs. The workshop will focus on three major themes: i) space-time discretization methods for PDEs; ii) co-design principles for the next generation of PDE solvers; and iii) real-world applications for these advanced solvers, ranging from fluid dynamics and Earth system modeling to plasma-based energy systems to biomedical simulations and personalized medicine.