The 25th International Computing and Combinatorics Conference (COCOON 2019) will be held in Xian, China during July 29-31, 2019. Original research papers in the areas of algorithms, theory of computation, computational complexity, and combinatorics related to computing are solicited. In addition to theoretical results, we are particularly interested in submissions that report on experimental and applied research of general algorithmic interest. Special consideration will be given to research that is motivated by real-world problems.