Following the tradition of the previous NuSYM symposia, NuSYM2019 is aimed to host synergies between the studies of nuclear structure, of nuclear reactions and of astrophysics, including new exciting ideas and all possible breakthroughs. The nuclear symmetry energy and its density dependence are known to govern to a large extent the physics of nuclear masses and radii, the collective excitations at moderate excitation energies, up to the dynamics and observables of the high-energy heavy-ion collisions that explore regimes characterized by higher densities and isospin asymmetry of nuclear matter, especially, with radioactive beams. Last but not least, the understanding of the density dependence of nuclear symmetry energy is of paramount importance in the context of the forefront research related to the astrophysical modelling of the stellar and explosive nucleosynthesis, of supernovae and kilonovae (first observed in the aftermath of GW170817), as well as of the properties of neutron stars and their mergers.