In recent years interdisciplinary approaches have changed the view on lysosomes as a purely degradative compartment towards central players in adaptive responses to metabolic, developmental and environmental cues and in the interplay with the autophagy pathway. In this international symposium we have gathered scientists from around the world to share their interest in molecular mechanisms of lysosomal homeostasis and regulation of autophagy. The scientific program includes invited lectures, short talks selected from submitted abstracts on the basis of scientific merit and relevance, and poster sessions. The symposium is limited to 160 participants. About the organizers: The Research Unit FOR2625 is supported by the German Research Foundation (DFG) and its research aims at elucidating the molecular mechanisms of maintaining lysosomal homeostasis and the adaptive regulatory mechanisms to compensate lysosomal dysfunctions (see www.for2625-lysosomes.de for detailed information).
Topics: Lysosomal genes, Lysosomal proteins and biogenesis, Lysosomal ion homeostasis, Organelle degradation, Ubiquitin-dependent turnover of endomembranes, Lysosomes and bacterial infection, Phosphoinositide signaling, mTORC1 signaling, Autophagy genes and proteins, Autophagy-related pathways, ER remodelling