EMBO Practical Course — Practical integrative structural biology

This EMBO practical course will give a practical introduction to integrative structural biology. Through lectures and hands-on practicals, the participants will learn about the fundamentals of X-ray crystallography, cryo-EM, small-angle X-ray scattering, NMR, and structural mass spectrometry. The invited tutors will show how to analyze and interpret the experimental data, and how to use the data for building structural models across different resolution scales. The course will also explore how experimental and computational methods aiming at resolving dynamics can be integrated to characterize flexibility in macromolecular structures. Finally, we will discuss the future of integrative structural biology approaches in light of the most recent advances in experimental and computational methods.