The JINA-CEE Frontiers in Nuclear Astrophysics Meeting will be held on May 25-27, 2022 at Embassy Suites South Bend/Notre Dame, 1140 East Angela Blvd., South Bend, IN 46617, USA. The meeting will be preceded by a two-day workshop for junior researchers on May 23-24 at the same location. This is the tenth in a series of former JINA and now JINA-CEE meetings that brings together JINA-CEE participants, collaborators, and other interested researchers in nuclear physics, astronomy, and astrophysics to discuss progress and future directions related to the understanding of the origin of the elements and neutron stars. This year, the Frontiers Meeting will also be the stage for the first IReNA collaboration meeting.