The chirality induced spin selectivity effect is a quantum phenomenon that is based on chirality, spin-orbit coupling, particle-particle interactions, and compositeness. However, exactly how these aspects are brought together and results in the CISS effect is a work under construction and much debate. While the outstanding issue of the foundations of the chirality induced spin selectivity effect has yet to be solved, novel direction are outlined in the community, new implications of the effect are being discovered Hence, within the scope of the workshop, these questions, among several others, will be discussed, with the aim to reach some clarification. Leading experts working in the field of the chirality induced spin selectivity effect as well as expert physicists, chemists, engineering and biology-oriented scientists aiming to focus research in this direction will provide lectures with a broad scope to facilitate a wider comprehension and open discussions of this enigmatic issue.