We invite submissions for the 41st Symposium on Principles of Database Systems, PODS'22. For over 40 years, PODS has been the leading conference in the theoretical aspects of data management, bringing together different communities such as logic and languages, knowledge representation, data mining, algorithms, web science, and privacy, with the aim of advancing the fundamentals of the tools we use to store, integrate, query, and analyze data in different contexts. The PODS community aims to provide a solid scientific basis for methods, techniques and solutions for the data management problems that continually arise in our data-driven society. Our goal is to develop solutions that ensure a high level of efficiency, scalability, expressiveness, robustness, flexibility, security, and privacy, among others.