The HHERF annual Human Health Summit (HHS) takes place in quarter four every year and the inaugural edition will be held completely virtual from 29th October to 1st November 2021. It brings together stakeholders from a wide range of sectors that impact human health, to build a World Integrated, Sustainable Health Eco-System (WISHES). The HHS is designed to be the first event with a unique focus on delivering changes for human health systems. The goal will be to reach a deep, scientific, and systematic understanding of current health challenges.