We are very pleased to announce the 15th conference on computer simulation of radiation effects in solids. Held every two years, COSIRES is a leading venue for presenting and discussing recent advances in the computational investigation of materials phenomena caused or influenced by all forms of irradiation. A field that connects cascade formation to irradiation creep is necessarily at the forefront of computational and experimental materials science, often driving innovation in advanced techniques across a vast range of time and length scales.