Welcome to the DAGStat Conference 2022! The sixth conference of the Deutsche Arbeitsgemeinschaft Statistik will take place in Hamburg, from March 28 to April 1, 2022. The conference is hosted by the Universität Hamburg in close cooperation with Universitätsklinikum Hamburg-Eppendorf and Helmut-Schmidt-Universität. The conference is also the 68th Biometric Colloquium of the German Region of the International Biometric Society (IBS-DR) and the 45th annual conference of the Gesellschaft für Klassifikation (GfKl) – Data Science Society.