On behalf of the Organizing Commission, it is our pleasure to invite you to attend the XXII International Symposium on Homogeneous Catalysis (XXII ISHC) to be held on 24-29 July 2022 in Lisbon, at Faculty of Sciences of the Universidade de Lisboa. All aspects of Homogeneous Catalysis, including metal complex catalysis, organo-, bio-, electro-, photo- and nanocatalysis, cooperative catalysis, heterogenized homogeneous catalysis, multiphase homogeneous catalysis, catalysis in unconventional media, noncovalent interactions in catalysis, mechanistic investigations, computational approaches, etc. will be highlighted in both already established and emerging fields.