In the proposed lecture course, we will bring together eminent researchers to learn and share the latest advances in the field of functional nucleic acids, basic principles, and cutting-edge applications in biology, human health, and diseases. The meeting will provide an opportunity for professionals with multidisciplinary backgrounds to review current developments, share ideas and challenges at the interface of chemistry, physics, and biology of nucleic acids therapeutics. This lecture course can thus serve as a powerful support to create a scientific environment that is conducive to interdisciplinary conversations and the exchange of new thoughts by bringing together the world's leading scientists with young researchers. This course will therefore continue to foster interactions and collaborations and encourage a new generation to join and explore the fascinating world of nucleic acid research.