Random Matrix Theory (RMT) is ubiquitous in the mathematical and physical sciences because of its broad range of applications and its predictive power, which allow accurate calculations and asymptotic analysis that are not accessible through traditional techniques. The interdisciplinary nature of RMT is epitomized by Prof. Jon Keating’s career, which has been characterized by the rare ability of initiating new areas of research by bringing together areas of mathematics that on the surface have little in common. This conference will feature leading mathematicians working at the interface of quantum chaos, analytic number theory, probability and random matrix theory.