Research Fellow in Structural Biology (FBSAS1015)

Are you interested in working in a productive, interdisciplinary team harnessing the power of heterologous expression in plants and cryo-electron microscopy to make major insights in structural virology through the determination of completely novel virus structures?

We are looking for an outstanding postdoctoral research fellow to make a BBSRC funded team working in structural virology. The team will consist of two post-doctoral researchers one at the University of Leeds based in the laboratory of Professor Neil Ranson (this post), and one focusing on heterologous expression in plants in the laboratory of Professor George Lomonossoff at the John Innes Centre (Norwich, UK).

You will be an experienced structural biologist, ideally with expertise in high-resolution cryo-EM. The programme plans to generate a significant number of novel, high resolution structures, and will require extensive expertise in atomic model building and refinement. With this in mind, a structural biologist with expertise in X-ray crystallography and the drive and commitment to learn cryo-EM would also be a strong candidate. As part of this role, you will determine the structures of virus like particles generated by heterologous expression of viral coat proteins in plants, and generate novel protein-based binding reagents for use in biotechnology, and diagnosis of authentic virus infections.

You will have a PhD (or be close to completion) in Structural Biology, Biochemistry or Biophysics. You will also have experience of using either X-ray crystallography, NMR, or cryo-EM to determine the 3D structures of biological macromolecules

Further information about the project and recent publications are available within the additional information document.

To explore the post further or for any queries you may have, please contact:

Professor Neil Ranson, Professor of Structural Molecular Biology

Tel: +44 (0)113 343 7065, email: n.a.ranson@leeds.ac.uk

Closing Date: 17 Oct 2017
Category: Research