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Institution: University of Southampton
United Kingdom
Retrieved : 2017-10-17 Expired
Description :

Developing OX40 and 4-1BB antibodies for Cancer Therapy (Funded by Bioinvent International)

Monoclonal antibodies (mAb) are now established as effective treatments for Cancer albeit with considerable potential for further improvement. The Cancer Sciences Unit in Southampton has a strong track record in basic and translational immunology including development of therapeutic mAb. 

BioInvent is a science-focused European biotech dedicated to development of antibody-based cancer immunotherapeutics.

Building on the recent successful generation and characterization of antibodies to the cell targets OX40 and 4-1BB, BioInvent and the Antibody and Vaccine Group within the Cancer Sciences Unit are now seeking a postdoctoral fellow to explore the molecular mechanisms by which antibodies to OX40 and 4-1BB promote anti-cancer immune responses in a variety of in vitro and murine in vivo models as we seek to develop these for translation into the clinic.

You will be motivated, educated in a relevant subject area and have practical laboratory experience. Ideally you will have research experience in standard cell-biological or immunological techniques and hold a Bachelor’s Degree and PhD or equivalent professional qualifications and experience. Prior experience with in vivo models and a current Home Office (HO) licence are also required. The post is fixed term for 12 months in the first instance with the possibility of further funding.

Please note: Interview's will be held on Thursday 16th November 2017 with a proposed start date of 1st December 2017.

Application procedure:

You should submit your completed online application form at www.jobs.soton.ac.uk. The application deadline will be midnight on the closing date stated above. If you need any assistance, please call Ita Holmes (Recruitment Team) on +44 (0) 23 8059 9002. Please quote reference 924917CM on all correspondence.

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.


Closing Date: 27 Oct 2017
Post Type: Education, Research & Enterprise





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