Research Fellow in Synthesis and Chemical Biology (MAPCH1103)

Are you an ambitious researcher looking for your next challenge? Do you have an established background in applying your synthetic chemistry skills to address biological problems? Do you want to further your career in one of the UKs leading research intensive universities?

As Research Fellow in Synthesis and Chemical Biology you will join an EPSRC-funded team focused on developing, validating and then exploiting new tools for discovering inhibitors of protein-protein interactions (PPIs). 

The Perturbation of Protein-Protein Interactions (PoPPI) project is a major £3.4 million five-year collaborative research programme led by Professor Andy Wilson, funded by the Engineering and Physical Sciences Research Council (EPSRC), and bringing together the University of Leeds, the University of Bristol, the Northern Institute of Cancer Research (Newcastle University) and drug discovery organisations, AstraZeneca and Domainex. This large and diverse programme focuses on developing, validating and exploiting new tools to discover inhibitors of PPIs. 

You will assist the Investigators in realising the vision for PoPPI by focussing on the design and synthesis of small-molecule probes for disease-relevant α-helix-mediated PPIs. The position will focus on the design and synthesis of small-molecule inhibitors.

This roles is being advertised alongside a Research Fellow position in Chemical Biology MAPCH1102 at the University of Leeds, and a Research Fellow position in Chemo/Bioinformatics at the University of Bristol.

To explore the post further or for any queries you may have, please contact: 

Adam Nelson, Professor of Chemical Biology 

Tel: +44 (0)113 343 6502; email: A.S.Nelson@leeds.ac.uk 

Closing Date: 02 Nov 2018
Category: Research