study of antixydant and antimicrobial potency of the leaves and pulp of Argania spinosa Algeria.of

Our study aims to assess the ability of the extract of the leaves and pulp of Argania spinosa L. Skeels  to scavenge free radicals , and to test its antimicrobial activity against various bacterial strains and a fungal strain : Candida albicans.

A phytochemical screening allowed knowing the phytoconsituants and targetingbya selective extractionthe principal families of thesemetabolites, includingtannins whose yieldwassignificant (0.6%),flavonoidsandsaponins based ontheir biological activity.

The reading of the results of the antibacterial and antioxidant activities showed that the extracts of the leaves were more active as antioxidants and antibacterial agents.

On testingthe antioxidant activityof the methanolic crude extract and tannins extractbyHPLTC, the resultwas positiveby the appearance ofyellow spotsin bothTLC platessprayedwithDPPH. The antioxydant activity of both extracts by a spectrophotometric quantification of DPPH showed a = 0.093mg/ml, CI50= 0.12 mg/ml for theethyl acetate fractionand tannins.

The extract flavonoids (ethyl acetate fraction) was found to be more potent against all bacteria strains and gave an interesting antibacterial activity against multi- resistant strain of Pseudomonas aeruginosa.

Keywords: Argania spinosa L.,antioxidant power, antimicrobial activity, extracts, flavonoids.