The conference will celebrate the life and the scientific achievements of Alvio Renzini, who turns 80 in July next year. Alvio’s extraordinary career spans over nearly 6 decades of amazing productivity and covers a great diversity of scientific topics, including stellar evolution, stellar populations in globular clusters, the Milky Way and nearby galaxies, elliptical galaxies, high-redshift star formation, theoretical modeling, observations. The scientific program is focused on the latest developments, both observationally and theoretically, in each of these topics with an emphasis on the interplay between the evolution of stellar populations in galaxy sub-structures, the evolution of the supermassive black hole, and the evolution of galaxies as systems across the cosmic time, including the physics of quenching.