The world is changing, along with perceptions. Many call for the improvement of mathematics teaching and learning, for both citizenry and STEM preparation. To achieve sustainable change, though, the focus needs to extend from individuals to systems. It is not enough to change one classroom or one course. Transformation requires change at all levels: in teaching, programmatic practices, and institutions. This workshop will bring together teachers and researchers from universities, community colleges, and K-12 schools to explore the reasons for and processes by which change in university mathematics departments is initiated, promoted, and sustained and lessons learned from change efforts in K-12. It will review what we know about change at all levels and reflect on stories of failure and success.