This EMBO Practical Course is designed to provide an overview of the latest aspects of ion channel and transporter research. Topics covered will include structural, functional and computational aspects, as well as more general themes, such as publishing and the role of women in science. Additionally, the course will feature didactic tutorials and some hands-on exercises. There will be ample opportunities for discussion and ad hoc interactions between students and lecturers. Lastly, the small town of Erice provides a relaxed and beautiful setting for the course.