Collective cell migration has paramount importance for embryogenesis, tissue repair and cancer progression. This phenomenon spans from the microscopic, molecular scale of cell signalling and cell-cell interactions, to the macroscopic, tissue-level scale of multicellular dynamics, and is amenable to both experimental and theoretical investigations. Collective cell migration is distinctly different from single cell migration in terms of its biological complexity and theoretical treatment. Our interdisciplinary program focuses on four key topics of collective cell migration, ranging from the molecular to the organismal level.
Topics: Cellular mechanisms of collective movement and metastasis, Mechanobiology of morphogenesis, Biophysical and mathematical modelling of collective movement and morphogenesis, In vivo imaging of migration and metastasis