LEAPS is the League of European Accelerator-based Photon Sources, a strategic consortium initiated by the Directors of the Synchrotron Radiation and Free Electron Laser (FEL) user facilities in Europe. Its primary goal is to actively and constructively ensure and promote the quality and impact of the fundamental, applied and industrial research carried out at their respective facility to the greater benefit of European science and society. In this context LEAPS will organize 14-19 May, 2023 the second LEAPS Conference aiming at bringing together the latest achievements from the Life Sciences user community with those from synchrotron radiation source development and instrumentation.